2025年

外科部

沈延盛

Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells

Molecular Cancer 2025; 24(1):1-18.

27.7

腫瘤醫學部/臨床醫學研究中心

蘇文彬

Redox disruption using electroactive liposome coated gold nanoparticles for cancer therapy

Nature Communications 2025;16:3253

14.7

內科部

林建中

Enhancing Lung Recovery: Inhaled Poly(lactic- co-glycolic) Acid Encapsulating FTY720 and Nobiletin for Lipopolysaccharide-Induced Lung Injury, with Advanced Inhalation Tower Technology

ACS Nano 2025;19(8):7634~7649

15.8

2024年

內科部
婦產部

許雅婷
沈孟儒

Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition

Journal Of Experimental & Clinical Cancer Research 2024;43:65

11.3

外科部

沈延盛

Extracellular Vesicular Analysis of Glypican 1 mRNA and Protein for Pancreatic Cancer Diagnosis and Prognosis

Advanced Science 2024;11(11):2306373

15.1

Germline mutations of homologous recombination genes and clinical outcomes in pancreatic cancer: a multicenter study in Taiwan

Journal of Biomedical Science 2024;31(1):21

11.0

臨床醫學研究中心

李青記

Prompt antimicrobial therapy and source control on survival and defervescence of adults with bacteraemia in the emergency department: the faster, the better

Critical Care 2024;28(1):176

15.1

內科部

柯文謙

內科部

楊貳翔
鄭修琦

10-Day versus 14-day bismuth quadruple therapy for first-line eradication of Helicobacter pylori infection: a randomised, open-label, non-inferiority trial

EClinicalMedicine 2024;70:102529

15.1

腫瘤醫學部/臨床醫學研究中心

蘇文彬

Polymeric nano-formulation of spectrum selective RTK inhibitor strengthens anti-cancer effects via immune remodeling by endoplasmic reticulum stress-modulating mitochondrial metabolism

Nano Today 2024;54:102070

17.4

APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance

Nucleic Acids Research  2024; 52(10):5676-5697

16.6

Harnessing the Power of Sugar-Based Nanoparticles: A Drug-Free Approach to Enhance Immune Checkpoint Inhibition Against Glioblastoma and Pancreatic Cancer

ACS Nano 2024; 18(42):28764-28781.

15.8

皮膚部

王德華

A point-of-care electrochemical biosensor for the rapid and sensitive detection of biomarkers in murine models with LPS-induced sepsis

Biosensors and Bioelectronics 2024;254:116202

12.6

皮膚部

許釗凱

TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts

Journal of Biomedical Science 2024; 31(1):12

11.0

職業及環境醫學部

簡玉雯

Discrepancies in dengue burden estimates: a comparative analysis of reported cases and global burden of disease study, 2010–2019

Journal of Travel Medicine 2024; 31(4):taae069

25.7

內科部

王竣令

Global trends in non-susceptibility rates of Streptococcus pneumoniae isolates to ceftriaxone: Data from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme, 2016-21

International Journal of Antimicrobial Agents 2024;63(2):107072

10.8

林建佑

Cardiac events and survival in patients with EGFR-mutant non–small cell lung cancer treated with osimertinib

JAMA Network Open 2024; 7(12):e2448364.

10.5

婦產部

許耿福

梁玉玲

Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer

Journal of Biomedical Science 2024;31(1):62

11.0

皮膚部

許釗凱

Dominant dystrophic epidermolysis bullosa is associated with glycolytically active GATA3+ T helper 2 cells which may contribute to pruritus in lesional skin

British Journal of Dermatology  2024; 191(2):252-260

11.0

2023年

內科部
婦產部

許雅婷
沈孟儒

Electrical Sympathetic Neuromodulation Protects Bone Marrow Niche and Drives Hematopoietic Regeneration during Chemotherapy

Small Methods 2023;7(6):e2201300

12.4

外科部

沈延盛

Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer

Nature Communications  2023;14(1):6692

16.6

外科部

沈延盛
趙盈瑞
王志榮

The experience of neoadjuvant chemotherapy versus upfront surgery in resectable pancreatic cancer: a cross sectional study

International Journal of Surgery 2023;109(9):2614~2623

15.3

腫瘤醫學部

蘇勇曄

內科部

王竣令
柯文謙

Geographic patterns of in vitro susceptibilities to tigecycline and colistin among worldwide isolates of Acinetobacter baumannii, Escherichia coli and Klebsiella pneumoniae: data from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme, 2016 to 2021

International Journal of Antimicrobial Agents 2023;62(3):106930

10.8

外科部

李榮順
王佳恩

Quantification of vessel separation using the carotid-jugular angle to predict the nerve origin of neck peripheral nerve sheath tumours: A pooled analysis of cases from the literature and a single-center cohort

International Journal of Surgery 2023;109(9):2704~2713

15.3

臨床醫學研究中心

蔡坤哲

Transthyretin attenuates TDP-43 proteinopathy by autophagy activation via ATF4 in FTLD-TDP

Brain 2023;146(5):2089~2106

15.255

內科部

薛俊盈

Improvement of Composite Kidney Outcomes by AKI Care Bundles: A Systematic Review and Meta-Analysis

Critical Care 2023;27(1):390

15.1

精神部

劉怡佳(職能治療師)

Occupational Evaluation of Community-Based Psychiatric Rehabilitation Outcomes in Individuals With Severe Mental Illnesses: A Ten-Year Retrospective Study

Asian Journal of Psychiatry 2023;81:103450

13.890

內科部
臨醫中心

李貽恒
林聖翔

Assessment of tyrosine kinase inhibitors and survival and cardiovascular outcomes of patients with non-small cell lung cancer in Taiwan

JAMA Network Open 2023;6(5):e2313824

13.360

Association of statin use with cancer- and noncancer-associated survival among patients with breast cancer in Asia

JAMA Network Open 2023;6(4):e239515

13.360

病理部

蔡慧頻(醫事檢驗師)

Acyclovir-resistant HSV-1 isolates among immunocompromised patients in southern Taiwan: Low prevalence and novel mutation

Journal of Medical Virology 2023;95(8):e28985

12.7

小兒部

何宗憲

 Developing magnetic barcode bead fluorescence assay for high throughput analyzing humoral responses against multiple SARS-CoV-2 variants

Biosensors and Bioelectronics 2023;241:115709

12.6

耳鼻喉部

張展旗

Single-sized N-functionality graphene quantum dot in tunable dual-modality near infrared–I/II illumination detection and photodynamic therapy under multiphoton nonlinear excitation

Biosensors and Bioelectronics 2023;241:115648

12.6

外科部

賴昭翰

Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases

Theranostics 2023;13(12):4059~4078

12.4

臨床醫學研究中心

洪澤民

Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR‑186‑5p/EGFR and miR‑497‑5p/IGF1R axes in non‑small cell lung cancer

Journal Of Experimental & Clinical Cancer Research 2023;42(1):283

11.3

MiR-455-5p suppresses PDZK1IP1 to promote the motility of oral squamous cell carcinoma and accelerate clinical cancer invasion by regulating partial epithelial-to-mesenchymal transition

Journal Of Experimental & Clinical Cancer Research 2023;42(1):40

11.3

內科部

王崇任

Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus

Journal of Biomedical Science 2023;30(1):78

11.0

復健部

連偉志

Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation

Bioengineering & Translational Medicine 2023;8(1):e10346

10.684

感染管制中心/內科部

李南瑤
翁子評

Integration of antimicrobial stewardship intervention with rapid organism identification improve outcomes in adult patients with bloodstream infections

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2023;56(1):57~63

10.273

內科部

鄭斌男

Interdependence of glycemic and lipid modulation in cured chronic hepatitis C patients by direct-acting antiviral agents

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2023;56(1):20~30

10.273

小兒部

沈靜芬
謝奇璋

Pre-existing humoral immunity and CD4+ T cell response correlate with cross-reactivity against SARS-CoV-2 Omicron subvariants after heterologous prime-boost vaccination

Clinical Immunology  2023;251:109342

10.190

外科部

陳柏全

HER2 amplification in colorectal cancer with brain metastasis: a propensity score matching study

European Journal of Cancer 2023;181:62~69

10.002

腫瘤醫學部

葉裕民
陳海雯

內科部

劉嚴文

HLA-Ehigh/HLA-Ghigh/HLA-IIlow Human iPSC-Derived Cardiomyocytes Exhibit Low Immunogenicity for Heart Regeneration

Advanced Healthcare Materials 2023;12(29):e2301186

10.0

2022年

外科部

沈延盛

Tumor‑associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling

Journal of Biomedical Science 2022;29(1):99

12.771

Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy

Theranostics 2022;12(1):340~361

11.556

內科部

柯文謙

Immunogenicity and safety of homologous and heterologous ChAdOx1-S and mRNA-1273 vaccinations in healthy adults in Taiwan

Journal of Clinical Virology 2022;150:105156

14.481

The emergence of Clostridioides difficile PCR ribotype 127 at a hospital in northeastern Taiwan

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(5):896~909

10.273

Trend in healthcare-associated infections due to vancomycin-resistant Enterococcus at a hospital in the era of COVID-19: more than hand hygiene is needed

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(6):1211~1218

10.273

內科部

蔡進相
柯文謙

Changing epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men

Emerging Microbes & Infections 2022;11(1):498~506

19.568

內科部

李明吉
柯文謙

Species identification and antifungal susceptibility of uncommon blood yeast isolates

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(1):130~137

10.273

內科部

柯文謙
李仁傑
陳柏齡

Causes of death among dengue patients causes of death among hospitalized adults with dengue fever in Tainan, 2015: Emphasis on cardiac events and bacterial infections

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(2):207~214

10.273

腫瘤醫學部/臨床醫學研究中心

蘇文彬

Atomically dispersed golds on degradable zero-valent copper nanocubes augment oxygen driven Fenton-like reaction for effective orthotopic tumor therapy

Nature Communications 2022;13(1):7772

17.694

Polyaniline-Based Glyco-Condensation on Au Nanoparticles Enhances Immunotherapy in Lung Cancer

ACS Applied Materials ＆ Interfaces 2022;14(21):24144~24159

10.383

Chemical Structure and Shape Enhance MR Imaging Guided X-ray Therapy Following Marginative Delivery

ACS Applied Materials ＆ Interfaces 2022; 14(11):13056-13069

10.383

內科部

陳嫈文
陳柏齡

Risk of non-typhoidal Salmonella vascular infections is increased with degree of atherosclerosis and inflammation: A multicenter study in southern Taiwan

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(3):474~481

10.273

內科部

李南瑤
柯文謙

Respiratory etiological surveillance among quarantined patients with suspected lower respiratory tract infection at a medical center in southern Taiwan during COVID-19 pandemic

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(3):428~435

10.273

內科部

李南瑤

A multicenter cohort study of severe dengue and critically ill influenza patients with elevated cardiac troponin-I: Difference clinical features and high mortality

Travel Medicine and Infectious Disease 2022;47:102281

20.441

內科部

李南瑤
蔡文嘉
羅景霳

Antimicrobial treatment of monomicrobial phenotypic carbapenem-resistant Klebsiella pneumoniae bacteremia: Two are better than one

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(6):1219~1228

10.273

內科部

鄭斌男

Entecavir Prevents HBV Reactivation During Direct Acting Antivirals for HCV/HBV Dual Infection: A Randomized Trial

Clinical Gastroenterology and Hepatology 2022;20(12):2088~2808

13.576

眼科部

洪嘉鴻
蘇鈺宸

Comparison of Sodium-Glucose Cotransporter 2 Inhibitors vs Glucagonlike Peptide-1 Receptor Agonists and Incidence of Dry Eye Disease in Patients With Type 2 Diabetes in Taiwan

JAMA Network Open 2022;5(9):e2232584

13.366

精神部

陳柏熹

 Generational synaptic functions of GABAA receptor β3 subunit deteriorations in an animal model of social deficit

Journal of Biomedical Science 2022;29(1):51

12.771

泌尿部

胡哲源

Interruption of the long non-coding RNA HOTAIR signaling axis ameliorates chemotherapy-induced cachexia in bladder cancer

Journal of Biomedical Science 2022;29(1):104

12.771

內科部

王崇任

Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Journal of Biomedical Science 2022;29(1):62

12.771

腫瘤醫學部

蔡慧珍

PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation

Journal of Biomedical Science 2022;29(1):92

12.771

內科部

楊思雋

Economic analysis of exclusionary EGFR test versus up-front NGS for lung adenocarcinoma in high EGFR mutation prevalence areas

Journal of the National Comprehensive Cancer Network 2022;20(7):774~782

12.693

腫瘤醫學部

張光裕

SH3GLB1‑related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma

Journal Of Experimental & Clinical Cancer Research 2022;41(1):220

12.658

小兒部

張毓珊
林其和

Postnatal Dexamethasone Therapy Impairs Brown Adipose Tissue Thermogenesis and Autophagy Flux in Neonatal Rat Pups

Theranostics 2022;12(13):5803~5819

11.600

臨醫中心

蔡曜聲

臨床醫學研究中心

洪澤民

α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer

Theranostics 2022;12(3):1173~1186

11.556

小兒部
家庭醫學部

蔡孟哲
李芷婷

Reciprocal peer network processes on substance use and delinquent behavior in adolescence: Analysis from a longitudinal youth cohort study

International Journal of Mental Health and Addiction 2022;2022:1~14

11.555

精神部

陳柏熹

Associations among smartphone app-based measurements of mood, sleep and activity in bipolar disorder

Psychiatry Research 2022;310:114425

11.225

內科部

林峻宇

Time-dependent Analysis of Risk of New-onset Heart Failure among Patients with Polymyositis and Dermatomyositis

Arthritis and Rheumatology 2022;74(1):140~149

10.995

小兒部

何宗憲

Development of SARS-CoV-2 variant protein microarray for profiling humoral immunity in vaccinated subjects

Biosensors and Bioelectronics 2022;204:114067

10.618

精神部

陳高欽
楊延光

Striatal dopamine D2/3 receptors in medication-naïve schizophrenia: an [123I] IBZM SPECT study

Psychological Medicine 2022;52(14):3251~3259

10.592

小兒部

沈靜芬

Outbreak of respiratory syncytial virus subtype ON1 among children during COVID-19 pandemic in Southern Taiwan

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(6):1168~1179

10.273

小兒部

沈靜芬
劉清泉

The epidemiology, clinical characteristics, and macrolide susceptibility of Mycoplasma pneumoniae pneumonia in children in Southern Taiwan, 2019-2020

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(4):611~619

10.273

內科部

曾進忠

Escherichia coli FimH adhesins act synergistically with PapGII adhesins for enhancing establishment and maintenance of kidney infection

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(1):44~50

10.273

內科部

林威宏

Escherichia coli urinary tract infections: host age-related differences in bacterial virulence factors and antimicrobial susceptibility

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(2):249~256

10.273

病理部

蔡慧頻醫事檢驗師

Novel Software for High-level Virological Testing: Self-Designed Immersive Virtual Reality Training Approach

Journal Of Medical Internet Research 2023;25:e44538

7.4

Highly-specific aptamer targeting SARS-CoV-2 S1 protein screened on an automatic integrated microfluidic system for COVID-19 diagnosis

Analytica Chimica Acta 2023;1274:341531

6.2

RNA Interference Approach Is a Good Strategy against SARS-CoV-2

Viruses-Basel 2023;15(1):100

5.8

Simultaneous detection of SARS-CoV-2 and influenza A/B viruses on an electromagnetically-driven, integrated microfluidic system

Sensors and Actuators B: Chemical 2024; 410:135647.

8.0

藥劑部
內科部

鄭靜蘭藥師
莊喬雄醫師

Suboptimal outcomes and retreatment rate of patients with crohn’s disease affter forced discontinuation of biologics: a nationwide population-based study

Clinical Pharmacology & Therapeutics 2023;114(4):914~921

6.7

藥劑部

鄭靜蘭藥師

Comparative effectiveness of bevacizumab versus cetuximab in metastatic colorectal cancer patients without primary tumor resection

Cancers 2022;14(9):2118

6.6

Sex difference in heart failure risk associated with febuxostat and allopurinol in gout patients

Frontiers in Cardiovascular Medicine 2022;9:891606

5.8

病理部

陳怡伶醫事檢驗師

Enhancing diagnosis of T-cell lymphoma using non-recombined T-cell receptor sequences

Frontiers in Oncology 2022;12:1014132

5.7

藥劑部

黃千惠藥師
鄭靜蘭藥師

Association Between Risk of Clostridium difficile Infection and Duration of Proton Pump Inhibitor or H2-Receptor Antagonist Use in Hospitalized Patients

Infectious Diseases and Therapy 2024;13(2):373~383

5.4

臨床創新研發中心

蘇建州博士

護理部

馮瑞鶯

Health services utilization and cost of abusive head trauma in Taiwan: A population-based retrospective matched cohort study

Child Abuse & Neglect 2022;128:105603

學門排名4.5%

Patterns and trajectories of children’s maltreatment experiences in Taiwan: Latent transition analysis of a nationally representative longitudinal study

Child Abuse & Neglect  2023;135:105951

學門排名4.5%

Development of a disaster preparedness training program for community leaders: Evidence from Taiwan

International Journal of Disaster Risk Reduction 2024;108:104517

5.0

陳佳德

Cold Application in Pain and Anxiety Reduction following Chest Tube Removal: A Systematic Review and Meta-Analysis

Journal of Clinical Nursing 2023;32(3-4):574~583

學門排名3.2%

孫婉娜

Nurses’ Knowledge and Skills After Use of an Augmented Reality App for Advanced Cardiac Life Support Training: Randomized Controlled Trial

Journal Of Medical Internet Research 2024; 26:e57327.

5.8

復健部

徐秀雲

Effects of an assist-as-needed equipped Tenodesis-Induced-Grip Exoskeleton Robot (TIGER) on upper limb function in patients with chronic stroke

Journal of NeuroEngineering and Rehabilitation 2024;21(1):5

5.2